Preventing and Treating Influenza

Title:

Peptides for inducing heterosubtypic influenza T cell responses

Category:

Therapeutic

NCS:

Inventors: Hoft

Summary:

This invention provides compositions and methods for generation of an anti-influenza immune
response. In particular, conserved T cell epitopes within matrix protein and nucleoprotein
components of influenza virus have been identified and further screened for those structures
that will bind either or both of HLA I and II molecules. Methods for vaccinating subjects with
formulations of such peptides for the treatment or prevention of influenza infection also are
described.

Patent:

U.S. pending

Manager:

Stephanie Kimzey, MBA

Office of Technology Management
Fusz Hall, Suite 253
Phone: 314-977-7731
kimzeysl@slu.edu